GluR4在单侧聋大鼠耳蜗核不同发育时间的表达~△
GluR4 Expression in Cochlear Nucleus of Rats with Single-side Deafness at Different Developmental Stages
原晶晶;闫占峰;周沫;葛鑫颖;刘锦峰;王鑫;巩政;张莹;刘思溟;王宁宇
1:北京中医药大学东直门医院
2:首都医科大学附属北京朝阳医院
摘要关键词基金项目(Foundation):作者参考文献1 Kaplan AB,Kozin ED,Remenschneider A,et al.Amblyaudia:review of pathophysiology,clinical presentation,and treatment of a new diagnosis[J].Otolaryngol Head Neck Surg,2016,154(2):247-55.
2 Zhou M,Yuan J,Yan Z,et al.Intrinsic and miniature postsynaptic current changes in rat principal neurons of the lateral superior olive after unilateral auditory deprivation at an early age[J].Neuroscience,2020,428:2-12.
3 刘锦峰，戴金升，王宁宇.单侧听觉剥夺对声源定位通路影响的研究进展[J].中华耳鼻咽喉头颈外科杂志，2017,52(2):136-142.
4 Popescu MV,Polley DB .Monaural deprivation disrupts development of binaural selectivity in auditory midbrain and cortex[J].Neuron,2010,65(5):718-731.
5 Chen Z,Yuan W.Central plasticity and dysfunction elicited by aural deprivation in the critical period[J].Front Neural Circuits,2015,9:26.
6 Dai J,Liu J,Zhou M,et al.Neurotransmitters and receptors changes in medial nucleus of the trapezoid body (MNTB) of early-developmental rats with single-side deafness[J].Med Sci Monit,2018,24:397-404.
7 Diering GH,Huganir RL.The AMPA receptor code of synaptic plasticity[J].Neuron,2018,100(2):314-329.
8 Gardner SM,Trussell LO,Oertel D.Correlation of AMPA receptor subunit composition with synaptic input in the mammalian cochlear nuclei[J].J Neurosci,2001,21(18):7428-7437.
9 Potashner SJ,Suneja SK,Benson CG.Altered glycinergic synaptic activities in guinea pig brain stem auditory nuclei afferent unilateral cochlear ablation[J].Hear Res,2000,147(1-2):125-136.
10 Sato K,Shiraishi S,Nakagawa H,et al.Diversity and plasticity in amino acid receptor subunits in the rat auditory brain stem[J].Hear Res,2000,147(1-2):137-144.
11 Petralia RS,Rubio ME,Wang YX,et al.Differential distribution of glutamate receptors in the cochlear nuclei[J].Hear Res,2000,147(1-2):59-69.
12 Antunes FM,Rubio ME,Kandler K.Role of GluA3 AMPA receptor subunits in the presynaptic and postsynaptic maturation of synaptic transmission and plasticity of endbulb bushy cell synapses in the cochlear nucleus[J].J Neurosci,2020,40(12):2471-2484.
13 Rubio ME,Matsui K,Fukazawa Y,et al.The number and distribution of AMPA receptor channels containing fast kinetic GluA3 and GluA4 subunits at auditory nerve synapses depend on the target cells[J].Brain Struct Funct,2017,222(8):3375-3393.
14 楚铜，金晓杰，王家东.大鼠单侧耳蜗损伤后蜗核中GluR2/3受体表达的变化[J].听力学及言语疾病杂志，2006,14(4):283-288.
15 Whiting B,Moiseff A,Rubio ME.Cochlear nucleus neurons redistribute synaptic AMPA and glycine receptors in response to monaural conductive hearing Loss[J].Neuroscience,2009,163(4):1264-1276.