不同预后的全聋型突发性聋患者治疗前失匹配负波的探讨

A Study of Mismatch Negativity in Patients with Total Deafness of Sudden Hearing Loss with Different Prognosis

朱斌;陈晨;张柳燕;关兵;徐丽

1:苏北人民医院耳鼻咽喉头颈外科

摘要
目的 探讨不同预后单侧全聋型突发性聋(简称突聋)患者失匹配负波(mismatch negativity, MMN)的特点,评估MMN与其预后的关系。方法 对51例单侧全聋型突发性聋患者在治疗前进行纯音测听(PTA)以及MMN检查,治疗10 d后再复查PTA,根据预后分为无效组、有效组,观察两组间MMN潜伏期及波幅的特点,并比较其与正常对照组(26例)的差异。结果 51例突聋患者和26例正常组均引出MMN波形,其中有效组(29例)、无效组(22例)MMN潜伏期均较正常组明显缩短,均有统计学差异(P<0.05),但无效组与有效组间MMN潜伏期无明显统计学差异(P>0.05);三组间波幅均无统计学差异(P>0.05)。结论 突聋患者MMN潜伏期明显缩短,无效组、有效组间MMN潜伏期、波幅没有差异。
关键词
突发性聋;失匹配负波;听觉皮层
基金项目(Foundation):
苏北人民医院科研基金资助项目(yzucms202026)
作者
朱斌;陈晨;张柳燕;关兵;徐丽
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