钙蛋白酶与内毛细胞带状突触噪声损伤的相关性研究
Correlation Study of Calpain and Noise-induced Cochlear Synaptopathy in Inner Hair Cells
蔡瑞捷;刘宏超;周卫军;刘辉辉;吴皓
1:上海交通大学附属第九人民医院耳鼻咽喉头颈外科
2:上海交通大学医学院耳科学研究所
3:上海市耳鼻疾病转化医学重点实验室
1 Parsons TD,Sterling P.Synaptic ribbon.Conveyor belt or safety belt[J].Neuron,2003,37(3):379-382.
2 Kujawa SG,Liberman MC.Adding insult to injury:cochlear nerve degeneration after "temporary" noise-induced hearing loss[J].J Neurosci,2009,29(45):14077-14085.
3 Sergeyenko Y,Lall K,Liberman MC,et al.Age-related cochlear synaptopathy:an early-onset contributor to auditory functional decline[J].J Neurosci,2013,33(34):13686-13694.
4 Fettiplace R,Hackney CM.The sensory and motor roles of auditory hair cells[J].Nat Rev Neurosci,2006,7(1):19-29.
5 Chen FQ,Zheng HW,Hill K,et al.Traumatic noise activates Rho-family GTPases through transient cellular energy depletion[J].J Neurosci,2012,32(36):12421-12430.
6 Heinrich UR,Maurer J,Mann W.Ultrastructural evidence for protection of the outer hair cells of the inner ear during intense noise exposure by application of the organic calcium channel blocker diltiazem[J].ORL J Otorhinolaryngol Relat Spec,1999,61(6):321-327.
7 Campbell RL,Davies PL.Structure-function relationships in calpains[J].Biochem J,2012,447(3):335-351.
8 Kanamori T,Kanai MI,Dairyo Y,et al.Compartmentalized calcium transients trigger dendrite pruning in Drosophila sensory neurons[J].Science,2013,340(6139):1475-1478.
9 Villegas R,Martinez NW,Lillo J,et al.Calcium release from intra-axonal endoplasmic reticulum leads to axon degeneration through mitochondrial dysfunction[J].J Neurosci,2014,34(21):7179-7189.
10 Yamaguchi T,Yoneyama M,Ogita K.Calpain inhibitor alleviates permanent hearing loss induced by intense noise by preventing disruption of gap junction-mediated intercellular communication in the cochlear spiral ligament[J].Eur J Pharmacol,2017,803:187-194.
11 Sheets L,Kindt KS,Nicolson T.Presynaptic CaV1.3 channels regulate synaptic ribbon size and are required for synaptic maintenance in sensory hair cells[J].J Neurosci,2012,32(48):17273-17286.
12 Wong HC,Zhang Q,Beirl AJ,et al.Synaptic mitochondria regulate hair-cell synapse size and function[J].Elife,2019,8:e48914.
13 Khimich D,Nouvian R,Pujol R,et al.Hair cell synaptic ribbons are essential for synchronous auditory signalling[J].Nature,2005,434(7035):889-894.
14 Singer W,Zuccotti A,Jaumann M,et al.Noise-induced inner hair cell ribbon loss disturbs central arc mobilization:a novel molecular paradigm for understanding tinnitus[J].Mol Neurobiol,2013,47(1):261-279.
15 Jing Z,Rutherford MA,Takago H,et al.Disruption of the presynaptic cytomatrix protein bassoon degrades ribbon anchorage,multiquantal release,and sound encoding at the hair cell afferent synapse[J].J Neurosci,2013,33(10):4456-4467.
16 Liu H,Peng H,Wang L,et al.Differences in calcium clearance at inner hair cell active zones may underlie the difference in susceptibility to noise-induced cochlea synaptopathy of C57BL/6J and CBA/CaJ mice[J].Front Cell Dev Biol,2020,8:635201.