等离子点状激发射频消融技术在猪声带部分切除术中的应用研究

Application of Radiofrequency Ablation with Plasma Spot Excitation in Partial Resection of Vocal Fold in Pig

刘婕妤;肖旭平;周恩;李京鲲;肖禹

1:湖南省人民医院(湖南师范大学附属第一医院)健康管理中心

2:湖南省人民医院(湖南师范大学附属第一医院)耳鼻咽喉头颈外科

摘要
目的 建立猪声带损伤模型,分析比较CO_2激光手术及低温等离子点状激发射频消融术对猪声带的损伤范围及声带损伤后修复模式。方法 15头猪(30侧声带),同一头猪的双侧声带分别为激光组和等离子组,分别用CO_2激光和低温等离子点状激发射频消融技术行声韧带下切除术,于术后第1天、术后第3、6、9、15周麻醉后各处死3头猪,取声带行HE染色,垂直测量两组声带水肿变性区深度和纤维组织厚度,比较两组术后声带损伤范围及声带修复过程。结果 术后第1天激光组水肿变性区深度较等离子组更深(P<0.01),术后第3、6、9周两组间差异无统计学意义(P>0.05)。两种术式术后第3周水肿变性区深度均小于术后第1天,术后第6周小于术后第3周(P<0.05);而术后第9周与术后第6周差异无统计学意义(P>0.05)。术后第15周等离子组声带固有层纤维组织厚度较激光组更薄(P<0.01)。结论 等离子点状激发射频消融技术对猪声带的损伤范围相对CO_2激光较小,术后修复情况两种手术方式无明显差异,而形成声带瘢痕时声带固有层的纤维组织厚度等离子组更薄。
关键词
低温等离子射频消融;点状激发;动物模型;喉部损伤修复
基金项目(Foundation):
湖南省卫生健康委员会一般指导课题(202107014091);; 长沙市科技局项目(kq2202442)
作者
刘婕妤;肖旭平;周恩;李京鲲;肖禹
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