信号传导及转录激活蛋白家族与听力损失的研究进展
Advances in the Study of the Signal Transducer and Activator of Transcriptions Family and Hearing Loss
王思龙;吴珂;孙一诺;江美旭;尹海燕;郭岩
1:济宁医学院基础医学院
1 Gentilin E,Simoni E,Candito M,et al.Cisplatin-Induced ototoxicity:updates on molecular targets[J].Trends Mol Med,2019,25(12):1123-1132.
2 Kalinec GM,Lomberk G,Urrutia RA,et al.Resolution of cochlear inflammation:novel target for preventing or ameliorating drug-,noise- and age-related hearing loss[J].Front Cell Neurosci,2017,11:192.DOI:10.3389/fncel.2017.00192.
3 Kishimoto-Urata M,Urata S,Fujimoto C,et al.Role of oxidative stress and antioxidants in acquired inner ear disorders[J].Antioxidants (Basel),2022,11(8):1469.
4 Sekulic-Jablanovic M,Wright MB,Petkovic V,et al.Pioglitazone ameliorates gentamicin ototoxicity by affecting the TLR and STAT pathways in the early postnatal organ of corti[J].Front Cell Neurosci,2020,14:566148.DOI:10.3389/fncel.2020.566148.
5 Butturini E,Carcereri de Prati A,Mariotto S.Redox regulation of STAT1 and STAT3 signaling[J].Int J Mol Sci,2020,21(19):7034.
6 Rah B,Rather RA,Bhat GR,et al.JAK/STAT signaling:molecular targets,therapeutic opportunities,and limitations of targeted inhibitions in solid malignancies[J].Front Pharmacol,2022,13:821344.DOI:10.3389/fphar.2022.821344.
7 Liang J,Wang D,Renaud G,et al.The stat3/socs3a pathway is a key regulator of hair cell regeneration in zebrafish [J].J Neurosci,2012,32(31):10662-10673.
8 Chen Q,Quan Y,Wang N,et al.Inactivation of STAT3 signaling impairs hair cell differentiation in the developing mouse cochlea[J].Stem Cell Reports,2017,9(1):231-246.
9 谢利红,王梦琳,唐安洲.内耳毛细胞再生及其信号通路的研究进展[J].听力学及言语疾病杂志,2018,26(5):547-550.
10 Setz C,Benischke AS,Pinho Ferreira Bento AC,et al.Induction of mitophagy in the HEI-OC1 auditory cell line and activation of the Atg12/LC3 pathway in the organ of Corti[J].Hear Res,2018,361:52-65.
11 Aburto MR,Sanchez-Calderon H,Hurle JM,et al.Early otic development depends on autophagy for apoptotic cell clearance and neural differentiation[J].Cell Death Dis,2012,3(10):e394.
12 Fang B.Xiao H Rapamycin alleviates cisplatin-induced ototoxicity in vivo[J].Biochem Biophys Res Commun,2014,448(4):443-447.
13 Zhong LX,Zhang Y,Wu ML,et al.Resveratrol and STAT inhibitor enhance autophagy in ovarian cancer cells[J].Cell Death Discov,2016,2:15071.DOI:10.1038/cddiscovery.2015.71.
14 Metge BJ,Mitra A,Chen D,et al.N-Myc and STAT interactor regulates autophagy and chemosensitivity in breast cancer cells[J].Sci Rep,2015,5(1):11995.
15 Levano S.Bodmer D loss of STAT1 protects hair cells from ototoxicity through modulation of STAT3,c-Jun,Akt,and autophagy factors[J].Cell Death Dis,2015,6(12):e2019.
16 Wu J,Ye J,Kong W,et al.Programmed cell death pathways in hearing loss:a review of apoptosis,autophagy and programmed necrosis[J].Cell Prolif,2020,53(11):e12915.
17 Xu X,Lai Y,Hua ZC.Apoptosis and apoptotic body:disease message and therapeutic target potentials[J].Biosci Rep,2019,39(1).BSR20180922.
18 Kaur T,Borse V,Sheth S,et al.Adenosine A1 receptor protects against cisplatin ototoxicity by suppressing the (NOX3/STAT1) inflammatory pathway in the cochlea[J].J Neurosci,2016,36(14):3962-3977.
19 Bhatta P,Dhukhwa A,Sheehan K,et al.Capsaicin protects against cisplatin ototoxicity by changing the STAT3/STAT1 ratio and activating cannabinoid (CB2) receptors in the cochlea[J].Sci Rep,2019,9(1):4131.
20 Rosati R,Shahab M,Neumann WL,et al.Inhibition of protein nitration prevents cisplatin-induced inactivation of STAT3 and promotes anti-apoptotic signaling in organ of Corti cells[J].Exp Cell Res,2019,381(1):105-111.
21 Borse V,Al Aameri RFH,Sheehan K,et al.Epigallocatechin-3-gallate,a prototypic chemopreventative agent for protection against cisplatin-based ototoxicity[J].Cell Death Dis,2017,8(7):e2921.
22 Supasai S,Aimo L,Adamo AM,et al.Zinc deficiency affects the STAT1/3 signaling pathways in part through redox-mediated mechanisms[J].Redox Biol,2017,11:469-481.
23 Butturini E,Cozzolino F,Boriero D,et al.S-glutathionylation exerts opposing roles in the regulation of STAT1 and STAT3 signaling in reactive microglia[J].Free Radic Biol Med,2018,117:191-201.
24 Rosati R,Shahab M,Ramkumar V,et al.Lmo4 deficiency enhances susceptibility to cisplatin-induced cochlear apoptosis and hearing loss[J].Mol Neurobiol,2021,58(5):2019-2029.
25 翟思佳.尹时华.与NLRP3炎性小体通路相关感音神经性聋的研究现状[J].听力学及言语疾病杂志,2022,30(1):101-104.
26 Wong AC.Ryan AF Mechanisms of sensorineural cell damage,death and survival in the cochlea[J].Front Aging Neurosci,2015,7:58.DOI:10.3389/fnagi.2015.00058.
27 Wilson T,Omelchenko I,Foster S,et al.JAK2/STAT3 inhibition attenuates noise-induced hearing loss[J].PLoS One,2014,9(9):e108276.
28 Huang J,Wang P,Li M,et al.Trichostatin a reduces cisplatin-induced ototoxicity through the STAT6 signaling pathway[J].Int J Mol Med,2015,36(2):493-500.