主观性耳鸣的中枢发病机制研究进展

Research Progress on Central Pathogenesis of Subjective Tinnitus

黄辛钊;武敬沂;彭华

1:南方医科大学第一临床医学院

2:南部战区总医院耳鼻咽喉头颈外科

摘要
耳鸣指在无外界声源时,耳内或颅内感知有一种或多种声音,仅患者能感觉到的耳鸣称为主观性耳鸣,其产生的中枢机制与听觉及非听觉中枢系统均有关系。中枢听觉传导通路中的中枢增益、神经元自发放电率增加、神经元之间同步性增加是耳鸣产生的主要因素。此外,非听觉中枢系统的体感通路以及边缘系统同样对耳鸣有着巨大的影响。主观性耳鸣的发病机制的研究可为其诊断及治疗提供进一步研究思路。
关键词
主观性耳鸣;中枢机制;研究进展
基金项目(Foundation):
广州市科技计划项目(201904010081);; 军队医学科技青年培育计划(20QNPY085);; 广东省重大科技专项资金项目(2013A022100035)
作者
黄辛钊;武敬沂;彭华
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黄辛钊武敬沂彭华