梅尼埃病基因研究进展

Advances in the genetic research of Meniere's disease

徐铭蔚;王珏;姚远;吴琼;张勤;杨军;金玉莲;张青

1:上海交通大学医学院附属新华医院耳鼻咽喉头颈外科上海交通大学医学院耳科学研究所上海市耳鼻疾病转化医学重点实验室

2:杭州市儿童医院耳鼻咽喉头颈外科

摘要
梅尼埃病是一种以膜迷路积水为主要病理改变的特发性内耳疾病。目前对该疾病相关基因的研究方法主要分为一代测序和二代测序两大类。本文总结近年来对梅尼埃病基因研究的文献报道,主要对家族性梅尼埃病中有重复家系验证的候选基因和散发性梅尼埃病中报道较多的候选基因进行综述。
关键词
家族性梅尼埃病;散发性梅尼埃病;候选基因
基金项目(Foundation):
国家自然科学基金资助项目(81970891、82171137);; 上海市科技创新行动计划(21S31900600);; 医企融合创新成果转化专项(SHDC2022CRD013)
作者
徐铭蔚;王珏;姚远;吴琼;张勤;杨军;金玉莲;张青
参考文献

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