RANK/RANKL/OPG信号通路在沙鼠外耳道胆脂瘤中的表达及意义
Expression and significance of RANK/RANKL/OPG signalling pathway in gerbil external ear canal cholesteatoma
何观文;林晓庆;郭秀琴;卢雯娴
1:福建医科大学宁德临床医学院
2:宁德师范学院附属宁德市医院耳鼻咽喉科福建省宁德市耳鼻咽喉科研究所
3:宁德市医院医疗集团屏南县总医院耳鼻咽喉科
4:中国人民解放军联勤保障部队第900医院耳鼻喉科
摘要关键词基金项目(Foundation):作者参考文献[1]刘婷,高雄辉,李鹏,等.耳内镜下不同分期外耳道胆脂瘤手术的疗效分析[J].听力学及言语疾病杂志,2020,28(5):531-534.
[2] XIANG G,QINGYUN W,XINLE Z,et al.Salvianolate ameliorates osteopenia and improves bone quality in prednisonetreated rheumatoid arthritis rats by regulating RANKL/RANK/OPG signaling[J].Frontiers in Pharmacology,2021,12710169-710169.DOI:10.3389/fphar.2021.710169
[3]王志凌,郭源源,张浩,等.骨免疫微环境中炎症因子诱导骨丢失的机制及免疫治疗研究进展[J].中国骨与关节杂志,2023,12(12):943-948.
[4]MARTA R,RICARDO S,MARIA G,et al. Analysis of salivary levels of IL-1β, IL17A,OPG and RANK-L in periodontitis using the 2017 classification of periodontal diseases—an exploratory observational study[J].Journal of Clinical Medicine,2023,12(3):1003.DOI:10.3390/jcm12031003.
[5]YE J,BIAN H Z,JING Z,et al.Fluoride-induced osteoporosis via interfering with the RANKL/RANK/OPG pathway in ovariectomized rats:oophorectomy shifted skeletal fluorosis from osteosclerosis to osteoporosis[J].Environmental Pollution,2023, 336:122407.DOI:10.1016/j.envpol.2023.122407.
[6]何观文,朱忠寿,魏日富,等.外耳道胆脂瘤临床特点及不同分期方案的比较研究[J].中华耳科学杂志,2020,18(1):112-116.
[7]GUANWEN H,RIFU W,LIWEN C,et al.Primary external auditory canal cholesteatoma of 301 ears:a singlecenter study[J].European Archives of Oto-Rhino-Laryngology,2021,279(4):1-8.
[8]BAUER J A,HUVE F,OLIVEIRA F H,et al.Mongolian gerbils as a model for the study of cholesteatoma:otoendoscopic as a diagnostic tool[J].Int Arch Otorhinolaryngol,2022,26(4):e643-e648.
[9]钱敏飞,张华,刘君,等.外耳道胆脂瘤临床特征及治疗[J].听力学及言语疾病杂志,2016,24(2):149-152.
[10]刘婷,刘雄辉,李鹏,等.耳内镜下不同分期外耳道胆脂瘤手术的疗效分析[J].听力学及言语疾病杂志,2020,28(5):531-534.
[11]WRIGHT H L,MCCARTHY H S,MIDDLETON J.RANK,RANKL and osteoprotegerin in bone biology and disease[J].Curr Rev Musculoskelet Med,2009,2(1):56-64.
[12]LUAN X,LU Q,JIANG Y,et al.Crystal structure of human RANKL complexed with its decoy receptor osteoprotegerin[J].J Immunol,2012,189(1):245-252.
[13]杨琴,万明,蒋正举,等.RNAKL及其相关因子在中耳胆脂瘤患者瘤组织中的分布和表达水平[J].中国老年学杂志,2014,34(18):5262-5263.
[14]GUPTA N,KANWAR N,ARORA A,et al.The interplay of rheumatoid arthritis and osteoporosis:exploring the pathogenesis and pharmacological approaches[J].Clin Rheumatol,2024,43:1421-1433.
[15]郑奔容,唐喜香,江博雄,等.2型糖尿病患者骨保护素和NF-κB受体活化因子配体与左室舒张功能障碍的相关研究[J].中山大学学报(医学科学版),2023,44(6):991-998.