听觉事件相关电位的晚期辨别负波成分研究进展

李琼;常淑林;单长硕;孙康宁;杨影;

1:滨州医学院听力与言语康复学专业

摘要
<正>听觉事件相关电位(auditory event related potential,AERP)通过给予声音刺激诱发大脑做出反应,探测大脑对声音刺激的早期注意加工和分辨能力,是研究听觉认知的重要工具,其潜伏期为50~750ms,属于长潜伏期诱发电位[1]。临床上为实用起见,将诱发电位分为外源性刺激相关电位和内源性刺激相关电位两大类,外源性刺激相关电位与感觉或运动功能相关,易受声音刺激的物理特性影响,如频率、声强等,包括P1、N1和P2等成分,这些成分潜伏期较短,属于早期诱发电位;内源性事件相关电位与认知功能相关,不完全受声音刺激的物理特性影响,包括N4(N400)、失匹配负波(mismatch negativity,MMN)、晚期辨别负波(late discriminatory negativity,LDN)和伴随负反应(contigent negative variaeion,CNV)等,这些成分潜伏期较长,属于晚期诱发电位成分(Walter,1964)。
关键词
基金项目(Foundation):
教育部人文社会科学基金青年项目(18YJC740128);; 山东省自然科学基金项目(ZR2018LH009);; 山东省研究生教育质量提升计划项目(SDYAL19164);; 国家级大学生创新训练项目(S202010440021);; 山东省大学生创新训练项目(S202010440058);; 滨州医学院大学生创新训练项目(202010440312,202010440311)
作者
李琼;常淑林;单长硕;孙康宁;杨影;
参考文献

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