统一帕金森病评定量表评估无言语障碍帕金森病患者的语音声学特征

Acoustic Analysis of Parkinsonian Speech without Perceptible Impairments in Terms of UPDRS

范萍;顾文涛;刘卫国;

1:南京师范大学文学院

2:南京医科大学附属脑科医院神经内科

摘要
目的 探讨统一帕金森病评定量表(unified Parkimson's disease rating seale, UPDRS)评估无言语障碍帕金森病患者的语音声学特征。方法 录制15例UPDRS量表评估无言语障碍的帕金森病患者(帕金森病组)和36例年龄匹配的健康成人(对照组)的朗读语音,提取语音的基频和元音共振峰特征,比较两组结果。结果 帕金森组的语音基频变异度(3.00±0.70 St)显著小于健康对照组(3.68±0.71 St)(P<0.01),而两组间元音发音指数无统计学差异(P>0.05)。结论 统一帕金森病评定量表评估无言语障碍的帕金森病患者因为中枢神经系统受损,言语基频的起伏变化趋于平缓。
关键词
帕金森病;言语障碍;基频;元音
基金项目(Foundation):
国家社会科学基金重大项目(13&ZD189);; 国家重点研发计划重点专项(2017YFC1310302);; 江苏高校哲学社会科学优秀创新团队建设项目(2017STD006)资助
作者
范萍;顾文涛;刘卫国;
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范萍顾文涛刘卫国