血常规相关指标与全频型突发性聋预后的相关性研究

The Correlation between Blood-routine Parameters and Prognosis of All Frequency Sudden Sensorineural Hearing Loss

何婧;陈家磊;钟时勋;

1:重庆医科大学附属第一医院耳鼻咽喉科

摘要
目的 分析全频型突发性聋患者治疗前后血常规指标的变化及其与疗效的相关性。方法 回顾性分析单侧全频型突发性聋患者102例的临床资料,根据疗效将患者分为有效组(59例)和无效组(43例),比较两组间治疗前后的血常规指标:白细胞(WBC)、中性粒细胞(NEUT)、单核细胞(MONO)、血小板(PLT)、淋巴细胞(LYM)、中性粒细胞/淋巴细胞比值(NLR)、单核细胞/淋巴细胞比值(MLR)、血小板/淋巴细胞比值(PLR)、平均血小板体积(MPV)、血小板分布宽度(PDW)和红细胞分布宽度(RDW)。结果 与治疗前相比较,无效组治疗后RDW、NLR水平明显升高(P<0.05),有效组治疗后LYM水平明显升高(P<0.05)。治疗后无效组NLR、MLR、RDW水平明显高于有效组(P<0.05),LYM水平明显低于有效组(P<0.05);治疗后一个月时两组间治疗前后的PLR有差异,治疗无效组(13例)PLR高于有效组(38例)(P<0.05)。治疗后的NLR、MLR、PLR、RDW、LYM水平与听力恢复程度相关,回归分析示开始治疗的时间晚、治疗后高NLR水平是全频型突发性聋预后不良的独立危险因素。结论 全频型突发性聋预后与开始治疗的时间、治疗后NLR、MLR、PLR、RDW、LYM水平相关。
关键词
突发性聋;血常规;预后
基金项目(Foundation):
作者
何婧;陈家磊;钟时勋;
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何婧陈家磊钟时勋