单侧梅尼埃病患者常规MRI内淋巴囊与前庭水管影像指征相关性分析

Correlation of Imaging Indices of the Endolymphatic Sac and Vestibular Aqueduct in Patients with Unilateral Ménière’s Disease on Non-enhanced MRI

雷萍;刘颖钊;冷杨名;李静;夏开军;刘波;

1:华中科技大学同济医学院附属协和医院放射科

2:华中科技大学同济医学院附属协和医院耳鼻咽喉科

摘要
目的 分析单侧梅尼埃病(Ménière’s disease, MD)患者常规磁共振成像(MRI)内淋巴囊与前庭水管(vestibular aqueduct, VA)的影像指征,探讨MD患者解剖因素的影像学特征。方法 纳入单侧MD患者(MD组)和健康者(对照组)各80例进行三维可变翻转角快速自旋回波序列(3-dimensional sampling perfection with application optimized contrast using different flip angle evolutions, 3D-SPACE)MRI,测量后半规管(posterior semicircular canal)垂直部至后颅窝(posterior fossa)距离(以“MRI-PP距离”表示),间接表示岩骨内淋巴囊大小,分析其与MRI影像中前庭水管(vestibular aqueduct, VA)可视性(MRI-VA可视性)之间的相关性。结果 (1)MD组患侧与健侧相比,MRI-PP距离(Z=-0.135,P=0.893)和MRI-VA可视性均无显著性差异(P=0.344);对照组耳间MRI-PP距离(t=-0.403,P=0.688)和MRI-VA可视性亦无显著性差异(P=0.302);(2)对于MRI-PP距离而言,MD组患侧[1.61(1.03,2.63)mm]及健侧[1.73(0.97,2.49)mm]均小于对照组右侧[2.20(1.79,3.19)mm]及左侧(2.49±1.26 mm);(3)对于MRI-VA可视性而言,MD组患侧(16.25%)及健侧(21.25%)均与对照组右侧(36.25%)及左侧(30%)无统计学差异。(4)合并分析两组数据,或单独分析MD组或对照组,均未发现MRI-PP距离对MRI-VA可视性的影响有统计学意义(均为P>0.05)。结论 单侧MD患者3D-SPACE序列MRI中PP距离与VA的可视性不具有相关性,提示这两个参数可独立应用于临床研究。
关键词
梅尼埃病;内淋巴囊;前庭水管;磁共振
基金项目(Foundation):
国家自然科学基金(81670930);; 湖北省自然科学基金(2021CFB547)
作者
雷萍;刘颖钊;冷杨名;李静;夏开军;刘波;
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