年龄相关性听力损失的易感基因研究进展

陈琪;赵立东;王秋菊;

1:解放军总医院耳鼻咽喉头颈外科医学部国家耳鼻咽喉疾病临床医学研究中心解放军耳鼻咽喉科研究所聋病防治北京市重点实验室

2:浙江中医药大学

摘要
<正>年龄相关性听力损失(age-related hearing loss, ARHL)又称为老年性聋(presbycusis),被定义为一种双侧对称性的、进行性的与年龄有关的感音神经性听力损失(SNHL),高频听力下降较为明显[1]。对尸头颞骨标本的研究发现,ARHL涉及多种听觉结构,包括耳蜗内外毛细胞机械传导退化(感音性老年性聋)、血管纹功能减退(代谢性老年性聋)以及听神经退化(神经性老年性聋),而现实中常表现为多种结构病变。
关键词
基金项目(Foundation):
国家重点研发计划项目(2020YFC2005200)的第一课题(2020YFC2005201)资助
作者
陈琪;赵立东;王秋菊;
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陈琪赵立东王秋菊