出生后不同发育阶段小鼠耳蜗Connexin30的表达
Expression of Connexin30 (Cx30) in the Postnatal Mouse Cochlear
刘文静;王文;王旭东;杨军;
1:东南大学附属中大医院耳鼻咽喉头颈外科
2:皖南医学院弋矶山医院耳鼻咽喉头颈外科
3:上海交通大学医学院附属新华医院耳鼻咽喉头颈外科
摘要关键词基金项目(Foundation):作者参考文献1 崔小缓，张延平，张晓强，等.GJB2基因条件敲除小鼠耳蜗凋亡相关基因表达差异研究[J].听力学及言语疾病杂志，2014,22(1):156-159.
2 Wu X,Tang W,Muly EC,et al.Expression pattern of connexin 26 and Connexin 30 in mature cochlea of the monkey [J].Biochem Biophys Res Commun,2019,518(2):357-361.
3 Mistrik P,Ashmore J.The role of potassium recirculation in cochlear amplification[J].Curr Opin Otolaryngol Head Neck Surg,2009,17(5):394-399.
4 Cohen-Salmon M,Regnault B,Cayet N,et al.Connexin30 deficiency causes instrastrial fluid-blood barrier disruption within the cochlear stria vascularis [J].Proc Natl Acad Sci USA,2007,104(15):6229-6234.
5 Qu Y,Tang WX,Zhou BF,et al.Early Developmental expression of connexin26 in the cochlea contributes to its dominate functional role in the cochlear gap junctions[J].Biochem Biophys Res Commun,2012,417(1):245-250.
6 Johnson SL,Ceriani F,Houston O,et al.Connexin-mediated signaling in nonsensory cells is crucial for the development of sensory inner hair cells in the mouse cochlea[J].J Neurosci.2017,37(2):258-268.
7 Ceriani?F,Hendry A,Jeng J,et al.Coordinated calcium signalling in cochlear sensory and non-sensory cells refines afferent innervation of outer hair cells[J].EMBO J,2019,38(9):1-19.
8 Jagger DJ,Forge A.Compartmentalized and signal-selective gap junctional coupling in the hearing cochlea[J].J Neurosci,2006,26(4):1260-1268.
9 何圆圆，杨军.新生大鼠耳蜗K?lliker器支持细胞ATP释放的机制[J].中华耳鼻咽喉头颈外科杂志，2015,50(1):43-49.
10 Wang HC,Bergles DE.Spontaneous activity in the deveoping auditory system Cell Tissue Res[J].2015,361(1):65-75.
11 Jagger DJ,Forge A.Connexins and gap Junctions in the inner ear——It's not just about K' recycling [J].Cell Tissue Res,2015,360(3):633-644.
12 Majumder P,Crispino G,Rodriguez L,et al.ATP-mediated cell-cell signaling in the organ of Corti:the role of connexin channels[J].Purinergic Signal,2010,6(2):167-187.
13 Forge A,Jagger DJ,Kelly JJ,et al.Connexin30-mediated intercellular communication plays an essential role in epithelial repair in the cochlea[J].Journal of Cell Science,2013,126(pt7):1703-1712.
14 Hibino H,Higashi-Shingai K,Fujita A,et al.Expression of an inwardly rectifying K+ channel,Kir5.1,in specific types of fibrocytes in the cochlear lateral wall suggests its functional importance in the establishment of endocochlear potentia[J].Eur J Neurosci,2004,19(1):76-84.
15 Matsunami T,Suzuki T,Hisa Y,et al.Gap junctions mediate glucose transport between GLUT1-positive and -negative cells in the spiral limbus of the rat cochlea [J].Cell Commun Adhes,2006,13(1-2):93-102.