伴终末期肾病突发性聋患者的临床特征及预后分析

王刚;邓国庆;梁俊涛;赵质彬;

1:海南省人民医院耳鼻咽喉头颈外科

2:海南医学院附属海南医院耳鼻咽喉头颈外科

摘要

目的探讨伴终末期肾病(end-stage renal disease, ESRD)突发性聋(突聋)患者的临床特征及听力预后。方法收集2010年1月到2019年1月住院治疗的35例(37耳)伴终末期肾病的突聋患者(ESRD组)的临床资料,另外选择同期住院治疗的369例(380耳)不伴终末期肾病的突聋患者作为对照组(非ESRD组),对比分析两组的临床特征及预后。结果 ESRD组患者的初诊听阈值、眩晕伴发率、高血压病和糖尿病伴发比例均高于非ESRD组,差异有统计学意义(P<0.05);ESRD组中,重度、极重度聋以及全聋型听阈曲线类型者分别占32.43%、32.43%和43.24%,均高于非ESRD组(分别为16.58%、17.37%和24.74%)(P<0.05);治疗结束后3个月,ESRD组的显效率及总体有效率分别为8.11%和54.05%,低于非ESRD组(分别为26.32%和76.32%)(P<0.05)。结论伴ESRD的突聋患者听力损失往往较重且常伴眩晕,听阈曲线以全聋型为主,听力预后较差。

关键词

终末期肾病;突发性聋;临床特征;预后分析

基金项目(Foundation):

海南省自然科学基金项目（819MS114）

作者

王刚;邓国庆;梁俊涛;赵质彬;

参考文献

1 刘丹，单春光，张玉波.突发性聋病因学研究进展[J].听力学及言语疾病杂志，2019,27(26):677-680.

2 段钰瑾，李大红，钟文伟，等.代谢综合征对突发性聋患者听力预后的影响[J].听力学及言语疾病杂志，2020,28(1):46-49.

3 Samanta R,Chan C,Chauhan VS.Arrhythmias and sudden cardiac death in end stage renal disease:epidemiology,risk Factors,and management [J].Can J Cardiol,2019,35(39):1228-1240.

4 Liu W,Meng Q,Wang Y,et al.The association between reduced kidney function and hearing loss:a cross-sectional study[J].BMC Nephrol,2020,21(1):145-145.

5 Wang IK,Wang CY,Muo CH,et al.Risk of sudden sensorineural hearing loss in patients with end-stage renal disease undergoing dialysis[J].Nephrology (Carlton),2017,22(5):397-402.

6 Lin C,Hsu HT,Lin YS,et al.Increased risk of getting sudden sensorineural hearing loss in patients with chronic kidney disease:a population-based cohort study [J].Laryngoscope,2013,123(3):767-773.

7 中华耳鼻咽喉头颈外科杂志编辑委员会，中华医学会耳鼻咽喉头颈外科学分会.突发性聋诊断和治疗指南(2015)[J].中华耳鼻咽喉头颈外科杂志，2015,50(6):443-447.

8 Li TY,Cheng PW,Young YH.Acute sensorineural hearing loss in hemodialysis patients[J].Acta Otolaryngol,2020,140(7):570-574.

9 Chou CL,Hsieh TC,Chen JS,et al.Sudden sensorineural hearing loss in hemodialysis patients could be a marker of pathogenic progression in the mortality and atherosclerotic events:a national cohort study[J].Otol Neurotol,2018,39(10):1241-1249.

10 Bergstrom L,Jenkins P,Sando I,et al.Hearing loss in renal disease:clinical and pathological studies[J].Ann OtolRhinol Laryngol,1973,82(4):555-576.

11 Rizvi SS,Holmes RA.Hearing loss from hemodialysis[J].Arch Otolaryngol,1980,106(12):751-576.

12 Wu RX,Chen CC,Wang CH,et al.Intratympanic steroid injection for sudden sensorineural hearing loss in a patient on hemodialysis[J].HemodialInt,2014,18(1):195-199.

13 Makita Y,Osato S,Onoyama K,et al.Idiopathic sudden sensorineural hearing loss in patients undergoing long-term haemodialysis[J].Int Urol Nephrol,1995,27(4):487-493.

14 王祥升，姜蕊蕊，宿江.突发性聋合并糖尿病患者的临床特征及预后分析[J].中国耳鼻咽喉颅底外科杂志，2020,26(1):80-83.

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终末期肾病突发性聋临床特征预后分析

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王刚邓国庆梁俊涛赵质彬