前庭水管口径及听力损失程度对LVAS患者ASNR引出率的影响

The Effect of the Orifice Diameter of the Vestibular Aqueduct and Hearing Loss Level on Acoustically Evoked Short Latency Negative Response in Children with Large Vestibular Aqueduct Syndrome

韩奎广;陈建勇;杨军;张勤;汪玮;沈佳丽;陈向平;

1:山东省兰陵县人民医院耳鼻咽喉科

2:上海交通大学医学院附属新华医院耳鼻咽喉头颈外科上海交通大学医学院耳科学研究所上海市耳鼻疾病转化医学重点实验室

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摘要

目的探讨大前庭水管综合征(large vestibular aqueduct syndrome, LVAS)患儿前庭水管开口口径及听力损失程度对声诱发短潜伏期负反应(acoustically evoked short latency negative response, ASNR)引出率的影响。方法回顾性分析26例(52耳)双侧单纯LVAS患儿的临床资料,在颞骨CT横断位上测量其前庭水管开口口径,根据气导短声听性脑干反应(ABR)反应阈将患者分为50～70 dB nHL组(18耳)、71～90 dB nHL组(15耳)和> 90 dB nHL组(19耳),分析ASNR引出与未引出者前庭水管开口口径及不同听力损失程度组ASNR引出率的差异。结果 26例(52耳)患者中ASNR总体引出率为48.07%(25/52耳);ASNR引出组(25耳)与未引出组(27耳)前庭水管开口口径的大小分别为6.9±1.4 mm和7.3±2.6 mm,差异无统计学意义(P>0.05);ABR反应阈为50～70 dB nHL组、71～90 dB nHL组和> 90 dB nHL组的ASNR引出率分别为33.33%(6/181)、46.67%(12/19)及63.16%(12/19),差异无统计学意义(P>0.05)。结论本组LVAS患者ASNR引出率为48.07%,ASNR引出不受前庭水管开口口径及听力损失程度的影响。

关键词

大前庭水管综合征;声诱发短潜伏期负反应;前庭水管开口口径;听力损失程度

基金项目(Foundation):

上海交通大学医学院附属新华医院院级临床培育基金重点项目（15CSK03）

作者

韩奎广;陈建勇;杨军;张勤;汪玮;沈佳丽;陈向平;

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