水通道蛋白1、2、5在膜迷路积水豚鼠耳蜗中的分布及表达研究
Distribution and Expression of AQP1, AQP2 and AQP5 Proteins in the Cochlea of Guinea Pigs with Membranous Labyrinthine Hydrops
冷辉;刘欣旭;张琦;
1:辽宁中医药大学附属医院耳鼻咽喉科
2:辽宁中医药大学
摘要关键词基金项目(Foundation):作者参考文献1 Ishibashi K,Hara S.Aquaporin water channels in mammals[J].Clinical and Experimental Nephrology,2009,13:107.
2 张星钰,董运鹏,张晓潮,等.梅尼埃病病因研究进展[J].听力学及言语疾病杂志,2016,24:491.
3 韩红蕾,张连山.醋酸去氨加压素诱导豚鼠膜迷路积水[J].中国听力语言康复科学杂志,2007(1):14.
4 Takeda T,Taguchi D.Aquaporins as potential drug targets for meniere’s disease and its related diseases[J].Handbook of Experimental Pharmacology,2009,190:171.
5 张倩,刘长健,高下,等.水通道蛋白在正常豚鼠中耳腔的表达及作用[J].中国耳鼻咽喉头颈外科,2008,15:457.
6 黄益灯,夏思文,吴龙军,等.晕动病发病中水通道蛋白1的变化[J].中国耳鼻咽喉头颈外科,2013,20:302.
7 阿不都许库尔·阿不力米提,阿力木江·吐拉洪,热娜古丽·努尔,等.肾缺血再灌注损伤大鼠肾内AQP2表达水平降低[J].中国组织化学与细胞化学杂志,2018,27:521.
8 黄巧,尹时华.内耳上皮钠通道、水通道蛋白与内淋巴代谢相关性的研究进展[J].山东大学耳鼻喉眼学报,2019,33:145.
9 Gu FM,Han HL,Zhang LS.Effects of vasopressin on gene expression in rat inner ear[J].Hear Res,2006,222:70.
10 Maekawa C,Kitahara T,Kizawa K,et al.Expression and translocation of aquaporin-2 in the endolymphatic sac in patients with Meniere′s disease[J].J Neuroendocrinol,2010,22:1157.
11 Hirt B,Penkova ZH,Eckhard A,et al.The subcellular distribution of aquaporin 5 in the cochlea reveals a water shunt at the perilymph-endolymph barrier[J].Neuroscience,2010,168:957.
12 Mhatre AN,Steinbach S,Hribar K,et al.Identification of aquaporin 5(AQP5) within the cochlear:cDNA cloning and in situ localization[J].Biochem Biophy Res Commun,1999,264:157.