听觉毛细胞发育再生研究进展

易英;郝香月;涂钰莹;龙孝斌;

1:南方医科大学珠江医院耳鼻咽喉头颈外科

摘要
<正>感音神经性听力下降可以由听觉传导通路中的耳蜗、听神经、脑干听觉通路和听觉中枢病变引起,其中耳蜗毛细胞极其脆弱,易受药源性、病原性以及噪声暴露等诸多因素损伤。现已有斑马鱼、鸟类和哺乳动物等多种脊椎动物模型被用于听觉系统、造血系统、心血管系统和神经系统的研究[1],斑马鱼因体型小、繁殖周期短、幼鱼透明、产卵量大、与人类基因同源性高,被广泛用于构建人类疾病模型和大规模的化学药物和遗传筛选[2, 3]。大量关于斑马鱼毛细胞再生的研究为哺乳动物毛
关键词
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作者
易英;郝香月;涂钰莹;龙孝斌;
参考文献

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易英郝香月涂钰莹龙孝斌