双模式助听儿童的皮层听觉诱发电位特征研究

Study on the Feature of Electroencephalogram Children with Cochlear Implant and Hearing Aids(Bi-mode)

刘一迪;郑琪;倪广健;耿江桥;刘海红;

1:国家儿童医学中心(北京)首都医科大学附属北京儿童医院耳鼻咽喉头颈外科儿童耳鼻咽喉头颈外科疾病北京市重点实验室

2:天津大学精密仪器与光电子工程学院

3:天津大学医学工程与转化医学研究院

4:河北医科大学附属河北省儿童医院耳鼻咽喉科

摘要
目的探讨人工耳蜗及助听器(hearing aids,HA)双模式助听与单独人工耳蜗植入(cochlear implant,CI)患者皮层听觉诱发电位(cortical auditory evoked potential, CAEP)中P1及失匹配负波(mismatch negativity, MMN)的分化特征,对双模式助听效果进行客观评价。方法双模式助听儿童7例(双模式使用时长均不少于6个月),在CI与助听器达到最佳助听模式后,分别在双模式及单侧CI两种助听模式下,以/ba1/、/ba4/(即/ba/一声和四声)作为标准刺激与偏差刺激声进行声场下CAEP测试,分析两种模式下P1波和MMN的潜伏期与幅值的差异。结果双模式助听下CAEP的P1的潜伏期、幅值以及MMN的潜伏期、幅值分别为159.29±31.80 ms、1.86±3.12μV、245.29±58.82 ms、-2.16±1.34μV;单侧CI助听时分别为172.00±43.84 ms、1.26±2.85μV、288.29±54.00 ms、-1.63±1.19μV。双模式助听下P1及MMN潜伏期较单侧助听CI时显著缩短(P<0.05),P1及MMN幅值较单侧CI时呈现增大趋势,但差异无统计学意义(P>0.05)。结论 CI及助听器双模式助听下CAEP的P1及MMN潜伏期较单侧CI助听时显著缩短,提示双模式助听下患者听觉辨别能力提高。
关键词
人工耳蜗植入;助听器;皮层听觉诱发电位;双模式
基金项目(Foundation):
作者
刘一迪;郑琪;倪广健;耿江桥;刘海红;
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