婴儿不同频率短纯音听性脑干反应正常值研究

Study on Normal Value of Different Frequencies of Tone Bursts Auditory Brainstem Response in Infants

沈佳丽;陈建勇;汪玮;王璐;马孝宝;张勤;沈敏;梅玲;陈向平;杨军;

1:上海交通大学医学院附属新华医院耳鼻咽喉头颈外科

2:上海交通大学医学院耳科学研究所

3:上海市耳鼻疾病转化医学重点实验室

摘要
目的建立听力正常婴儿不同频率气导短纯音听性脑干反应(tone burst-ABR, tb-ABR)反应阈的正常参考值;并探讨不同频率tb-ABR反应阈与气导短声ABR(click-ABR)反应阈的相关性,为婴儿不同频率听力损失的早期诊断和评估提供参考。方法对30例(60耳)2~6月龄的听力正常婴儿分别进行气导click-ABR以及0.5~4 kHz四个频率的tb-ABR测试,记录反应阈和阈值水平的潜伏期,分析结果。结果 0.5~4 kHz tb-ABR及click-ABR的反应阈分别为30.08±10.48、25.17±9.91、15.67±8.36、13.17±6.17和10.08±4.83 dB nHL;潜伏期分别为13.28±1.25、11.75±0.79、9.90±0.59、8.80±0.67和8.39±0.63 ms。click-ABR与0.5~1 kHz tb-ABR反应阈无相关性(P>0.05);click-ABR与2、4 kHz tb-ABR反应阈相关系数分别为0.346和0.389(P<0.05)。结论本研究建立了听力正常婴儿不同频率tb-ABR反应阈参考值,click-ABR主要与2、4 kHz tb-ABR反应阈存在相关性,不能反映低中频听力情况。
关键词
婴儿;短声听性脑干反应;短纯音听性脑干反应;正常值
基金项目(Foundation):
国家自然科学基金面上项目(81873689);; 上海交通大学医学院附属新华医院院级临床研究培育基金项目(17CSK03)
作者
沈佳丽;陈建勇;汪玮;王璐;马孝宝;张勤;沈敏;梅玲;陈向平;杨军;
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